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... require a heat-sealing machine to seal the pouches. They are more secure than self-seal pouches and are ideal for large-scale sterilization processes. Gusseted Sterilization Pouches : These pouches have extra material on the sides, allowing for more space ... ... methods are: Steam Sterilization: This method uses high-pressure steam to sterilize items. It is the most common method used in healthcare facilities and requires a pouch that is resistant to heat and moisture. Ethylene Oxide (ETO) Sterilization: This method ...